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    Please use this identifier to cite or link to this item: http://nccur.lib.nccu.edu.tw/handle/140.119/114861


    Title: Extracellular calcium concentration and channel activity involved in aminoglycoside-induced hair cell toxicity in the zebrafish lateral line
    Authors: 詹銘煥
    CHAN, MING-HUAN
    Wu, C.Y.
    Liu, C.F.
    Chen, H.H.
    Contributors: 神科所
    Date: 2016-10
    Issue Date: 2017-11-23 16:56:09 (UTC+8)
    Abstract: Introduction: Ototoxic damage often caused by antibiotic aminoglycosides leads to the loss of hair cells. Since aminoglycosides are effective at infection treatment, it is imperative to discover new approach to prevent hearing loss and permit safe use of aminoglycosides. The alterations in cytosolic calcium homeostasis play an important role in aminoglycoside-induced sensory hair cell death. However, the involvement of cytoplasmic membrane calcium channels in aminoglycoside ototoxicity is not clear.
    Relation: Toxicology Letters, Volume 259, Supplement, Page S202
    Data Type: article
    DOI 連結: https://doi.org/10.1016/j.toxlet.2016.07.484
    DOI: 10.1016/j.toxlet.2016.07.484
    Appears in Collections:[神經科學研究所 ] 期刊論文

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